PRODUCT CLASSIFICATION
Anxiolytic Peptide
ACNE-FREE
No
WATER RETENTION
No
HBR
No
HEPATOTOXICITY
No
AROMATIZATION
No
MANUFACTURER
Beligas
WAREHOUSE LOCATION
International Warehouse 3
ACTIVE INGREDIENT
Selank
In the dynamic world of biotechnology, groundbreaking substances are emerging, including innovative ?nootropics,? designed to enhance cognitive function.
One standout in this realm is Selank, previously known as ?TP-7.? This synthetic peptide is a meticulously crafted small protein, developed to promote mental clarity and well-being.
Renowned for its anti-anxiety properties, Selank helps improve learning capabilities and energize without the risk of addiction or side effects. Created through a collaboration between the Institute of Molecular Genetics and the V.V. Zakusov Research Institute of Pharmacology, this peptide is closely related to another compound, Semax.
Selank?s unique formulation combines a peptide sequence from tuftsin, a naturally occurring immune-modulating peptide, with additional elements designed to enhance its stability and efficacy.
Research indicates that both tuftsin and Selank can effectively reduce anxiety while boosting serotonin levels in animal studies, with Selank demonstrating superior effectiveness.
In Russia, Selank is officially approved for treating generalized anxiety disorder (GAD) and is also recognized as a nootropic. While it lacks FDA approval in the U.S., it remains accessible in various countries, often marketed as a ?nutritional supplement.?
How Selank WorksWhile the exact mechanisms of Selank are still being studied, it's believed to stabilize enkephalins?natural peptides that help modulate stress responses in the body.
Interestingly, one study on mice did not find enkephalin stabilization following Selank treatment, nor did it demonstrate significant anti-anxiety effects. However, some cellular research suggests that Selank may interact with GABA receptors, which are known for their sedative properties. A study indicated that Selank enhances activity in GABA-dependent inhibitory neurons, reducing overall brain activity and aligning with sedative effects.
Moreover, Selank may elevate levels of BDNF, an essential neurotrophic factor associated with learning and memory. It has also been shown to influence neurotransmitter levels?norepinephrine, dopamine, and serotonin?linked to motivation, focus, and enjoyment.
In one animal study, Selank increased norepinephrine while decreasing dopamine and serotonin levels, whereas another study indicated an increase in both norepinephrine and dopamine without altering serotonin levels. Thus, the precise effects and mechanisms of Selank warrant further investigation.
Potential Benefits of Selank: Anxiety ReliefA preliminary clinical trial involving 62 participants revealed that those treated with Selank experienced a notable reduction in anxiety symptoms, particularly among individuals with pre-existing anxiety disorders.
In another study of 60 patients with anxiety and phobias, lasting benefits were observed for up to a week after the final dose. Additionally, in a study of 70 anxiety patients, Selank enhanced the effects of phenazepam (an anti-anxiety medication banned in some U.S. states) while minimizing side effects like drowsiness and memory loss.
Animal research also supports Selank's efficacy in reducing anxiety in mice, with more significant benefits noted in those with higher initial anxiety levels. Remarkably, four weeks of treatment resulted in lasting anti-anxiety effects in rats.
While the evidence is still emerging, it suggests Selank may provide relief from anxiety. However, further research is essential to confirm its safety and effectiveness for human use. If you're experiencing anxiety, consult your healthcare provider about the potential benefits of Selank while adhering to their guidance.
Memory EnhancementOne trial suggested that Selank could stabilize memory traces in rats over 30 days, although the methods used for measurement remain unclear since memory traces are not distinctly identifiable in the brain.
Another study indicated that Selank may help preserve memory in monkeys. However, human studies are limited, and the effects on healthy individuals are not well understood, necessitating further research into long-term safety.
Recovery from Brain DamageIn a notable study, Selank was administered to rats with toxin-induced brain damage, reportedly restoring normal brain activity levels.
Depression ReliefSelank has shown promise in reducing depressive symptoms (as indicated by decreased immobility in forced swimming tests) in mice, with increased effectiveness noted at lower doses.
Antioxidant PropertiesPreliminary animal studies suggest that Selank injections elevate antioxidant levels in the livers of stressed mice.
Blood CirculationIn a study involving sedated cats, Selank significantly lowered blood pressure by around 30% for three minutes and increased blood flow to the brain by approximately 24% for ten minutes. Though these findings hint at short-term cardiovascular benefits, their clinical significance remains uncertain, especially without confirmation in healthy human subjects.
Alleviating Alcohol WithdrawalAlcohol withdrawal is often accompanied by anxiety. In a study where rats were given a 10% ethanol solution for 24 weeks, Selank reportedly alleviated anxiety levels after 48 hours of withdrawal.
Weight Control and Cholesterol ManagementIn one animal study, rats on a high-fat diet exhibited a 35% reduction in weight gain with Selank treatment. Additionally, their total cholesterol levels dropped by over 58%, coupled with a 23.5% decrease in blood glucose levels.
Potential Cancer TherapyIn an animal study, breast cancer-infected mice treated with daily doses of Selank showed slower tumor growth and increased longevity compared to untreated controls. However, these preliminary results do not imply Selank can replace standard cancer therapies, and extensive research is necessary to validate its efficacy in cancer treatment.
Reducing Spleen InflammationPost-treatment with Selank, mice exhibited elevated levels of various inflammatory response genes in their spleens, indicating potential protective effects against inflammation-related damage.
Ulcer ManagementSelank has demonstrated the ability to reduce stomach ulcer size in animal models, with some researchers proposing that it promotes lymph flow to the stomach, essential for immune function. Yet, further human studies are required to confirm these effects and understand their underlying mechanisms.
Immune Function EnhancementSelank has been shown to increase IL-6 production in blood cells from individuals with depression. IL-6 plays a crucial role in inflammation and immune responses. Additionally, in cell-based studies, Selank appeared to promote the release of interferons, vital anti-viral agents. However, one animal study involving virus-infected mice did not demonstrate any antiviral benefits, raising questions about this potential application.

