Duphaston

PRODUCT CLASSIFICATION Progesterone Agonist
RECOMMENDED DOSAGE 10-30 mg per day
ACNE INCIDENCE None
WATER RETENTION None
HBR (Hormonal Breakthrough Response) Possible
HEPATOTOXICITY RISK Yes
AROMATIZATION None
MANUFACTURER Abbott
STORAGE LOCATION International Warehouse 2
ACTIVE INGREDIENT Dydrogesterone

Duphaston is a highly effective medication featuring dydrogesterone as its active ingredient. As a classified progesterone agonist, it plays a crucial role in reducing the risk of endometrial hyperplasia.

This versatile medication is commonly prescribed for various conditions, including:

• Irregular menstrual cycles
• Dysmenorrhea (painful menstrual periods)
• Endometriosis
• Infertility

When combined with estrogen, Duphaston can also be beneficial in treating secondary amenorrhea (the absence of menstrual periods for six months or longer) and is effective in managing heavy and irregular bleeding.

Before using Duphaston, be aware of the following contraindications:

• Allergic reactions to dydrogesterone or similar medications. If you notice symptoms such as:
• skin rash,
• itchy skin,
• redness,
• swelling, or difficulty breathing, seek immediate medical assistance.
• Individuals with deep vein thrombosis (a blockage in veins).
• Patients with cancers that are influenced by progesterone or estrogen.
• Unexplained bleeding issues.
• Those with liver dysfunction, as Duphaston may impact liver health. If you experience symptoms like:
• pain in the upper right abdomen,
• loss of appetite,
• dark urine,
• jaundice (yellowing of skin and eyes), please consult your doctor promptly.
• Individuals suffering from depression.
• Patients with porphyria.

Regular breast self-exams are advised while using this medication due to an increased risk of breast cancer when combined with estrogen.

Duphaston is not recommended during pregnancy unless specifically prescribed by a healthcare professional. Additionally, this medication can be passed into breast milk, making breastfeeding inadvisable while taking Duphaston.

Your physician will determine the appropriate dosage for your needs. Please avoid self-medication.

Take the tablet whole with a glass of water; do not crush or chew it.

It's essential to avoid using Duphaston in conjunction with the following medications:

• Antiepileptic drugs such as:
• carbamazepine,
• phenytoin,
• phenobarbital, and others, as they may lower Duphaston?s effectiveness.
• HIV medications including:
• ritonavir,
• indinavir,
• saquinavir, among others.
• Herbal supplements like St. John's wort, sage, and ginkgo biloba, which can also diminish Duphaston levels and efficacy.

Always inform your doctor about all medications and herbal products you are taking.

Duphaston may cause side effects, which can include:

• Nausea
• Vomiting
• Headache
• Dizziness
• Weight gain
• Breast swelling
• Anemia
• Depression
• Fatigue
• Liver damage (loss of appetite, upper right abdominal pain, jaundice)
• Allergic reactions, among others.

If you experience any side effects, please notify your healthcare provider.